×

Advanced Systemic Mastocytosis: Considerations to Optimize Patient Management

Share with social media

While advanced systemic mastocytosis (SM) is a rare disorder, treatment options are still available; find out more about management strategies here!

Duration : 05:30:00 hours
Content provider : Akshaya Patra Foundation
Author name :
Matthew P. Giannetti Declaration of interests
Date launched at CMEPEDIA : July 4, 2024
Expiry date of course : May 7, 2025
Module size : 0.45MB
Price : ₹0.00 - ₹315.00(Some professional bodies apply charges, even if the content is free of cost. Log in to check whether your professional body does.)
Disclosure information:

Cmepedia requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

 

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Skill improvements:
knowledge, competence
Topic:
Oncology
Professional category:
General surgeon
Accreditation:
Category Accreditor Credits Accreditation details
Cardiologist, Emergency physician Accreditation Council for Continuing Medical Education 1 ACCME ACCME
General surgeon Royal Australasian College of Surgeons 5 RACS CPD Credit Cmepedia, designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim credit commensurate with their participation in the activity. Upon successful completion of this CME activity, including participation in the evaluation component, participants can earn up to 0.25 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. The number of MOC points earned will be equivalent to the amount of CME credits claimed for the activity. The CME activity provider is responsible for submitting participant completion information to ACCME to grant ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity
Cardiologist, Anesthesist, Emergency physician, Allergist, A...Read More Dutch Medical Society Model 1 DMSM Credits Dutch
Endorsements:
Endorsed by Accredited by Conversion credits
Bangalore XYZ council Dutch Medical Society Model 1 BXC Credits
Learning outcomes

For quite some time, our treatment armamentarium for patients with advSM consisted of incompletely effective therapies associated with significant toxicity. Now with the availability of targeted approaches, clinicians can provide patients with more efficacious and safer options. However, there is room for growth: the safety of current targeted approaches still needs to be improved, especially given severe adverse events such as intracranial hemorrhage. With this in mind, new trials are investigating novel agents (eg, BLU-263, bezuclastinib) that do not readily cross the blood-brain barrier, with the hope of reducing this potentially fatal event seen with current TKIs. Lastly, it is important to note that clinicians should consider referring patients with advSM to a specialized institution. Here, patients can receive individualized treatment and optimal care under the watch of a collaborative multidisciplinary team with expertise in managing symptoms and complications of advSM.

About the author

Author image

Matthew P. Giannetti

MD, Below are the relevant financial relationships:
Consultant or advisor for: Cogent Biosciences
Research funding from: Blueprint Medicines

Disclosed a conflict of interest. Their contributions are limited to non-clinical topics.

About the Peer Reviewer
5
0
4
0
3
0
2
0
1
0


×